The contributions are illustrative of the richness of the issues discussed and the breadth of the emerging themes, including innovative business models for building and infrastructure at district level, integrated sustainability assessment schemes for Positive Energy Districts, a material flow accounting model for regional metabolism, energy communities as a lever to promote historical and landscape values, optimized and electrified last-mile logistics, multi-criteria decision analysis tools to redefine center/periphery relationships, a framework for socio-spatial analysis related to social practices, design principles and communication technologies improving both indoor and outdoor public spaces, augmented nature-based solution coupling the green elements with the latest technologies to deliver healthier and more appealing cities.