Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis
David D'Argenio
2006 api. · The Springer International Series in Engineering and Computer Science 765. liburua · Springer Science & Business Media
Liburu elektronikoa
318
orri
reportBalorazioak eta iritziak ez daude egiaztatuta Lortu informazio gehiago
Liburu elektroniko honi buruz
Advanced Methods of Pharmacokinetic and Pharmocodynamic Systems Analysis Volume 3 is vital to professionals and academicians working in drug development and bioengineering. Both basic and clinical scientists will benefit from this work.
This book contains chapters by leading researchers in pharmacokinetic/pharmacodynamic modeling and will be of interest to anyone involved with the application of pharmacokinetic and pharmacodynamics to drug development.
The use of mathematical modeling and associated computational methods is central to the study of the absorption, distribution and elimination of therapeutic drugs (pharmacokinetics) and to understanding how drugs produce their effects (pharmacodynamics). From its inception, the field of pharmacokinetics and pharmacodynamics has incorporated methods of mathematical modeling, simulation and computation in an effort to better understand and quantify the processes of uptake, disposition and action of therapeutic drugs. These methods for pharmacokinetic/pharmacodynamic systems analysis impact all aspects of drug development. In vitro, animal and human testing, as well as drug therapy are all influenced by these methods. Modeling methodologies developed for studying pharmacokinetic/ pharmacodynamic processes confront many challenges. This is related in part to the severe restrictions on the number and type of measurements that are available from laboratory experiments and clinical trials, as well as the variability in the experiments and the uncertainty associated with the processes themselves.
The contributions are organized in three main areas: Mechanism-Based PK/PD, Pharmacometrics and Pharmacotherapy. Both professionals and academics will profit from this extensive work.
This book contains chapters by leading researchers in pharmacokinetic/pharmacodynamic modeling and will be of interest to anyone involved with the application of pharmacokinetic and pharmacodynamics to drug development.
The use of mathematical modeling and associated computational methods is central to the study of the absorption, distribution and elimination of therapeutic drugs (pharmacokinetics) and to understanding how drugs produce their effects (pharmacodynamics). From its inception, the field of pharmacokinetics and pharmacodynamics has incorporated methods of mathematical modeling, simulation and computation in an effort to better understand and quantify the processes of uptake, disposition and action of therapeutic drugs. These methods for pharmacokinetic/pharmacodynamic systems analysis impact all aspects of drug development. In vitro, animal and human testing, as well as drug therapy are all influenced by these methods. Modeling methodologies developed for studying pharmacokinetic/ pharmacodynamic processes confront many challenges. This is related in part to the severe restrictions on the number and type of measurements that are available from laboratory experiments and clinical trials, as well as the variability in the experiments and the uncertainty associated with the processes themselves.
The contributions are organized in three main areas: Mechanism-Based PK/PD, Pharmacometrics and Pharmacotherapy. Both professionals and academics will profit from this extensive work.
Baloratu liburu elektroniko hau
Eman iezaguzu iritzia.
Irakurtzeko informazioa
Telefono adimendunak eta tabletak
Instalatu Android eta iPad/iPhone gailuetarako Google Play Liburuak aplikazioa. Zure kontuarekin automatikoki sinkronizatzen da, eta konexioarekin nahiz gabe irakurri ahal izango dituzu liburuak, edonon zaudela ere.
Ordenagailu eramangarriak eta mahaigainekoak
Google Play-n erositako audio-liburuak entzuteko aukera ematen du ordenagailuko web-arakatzailearen bidez.
Irakurgailu elektronikoak eta bestelako gailuak
Tinta elektronikoa duten gailuetan (adibidez, Kobo-ko irakurgailu elektronikoak) liburuak irakurtzeko, fitxategi bat deskargatu beharko duzu, eta hura gailura transferitu. Jarraitu laguntza-zentroko argibide xehatuei fitxategiak irakurgailu elektroniko bateragarrietara transferitzeko.
