This volume constitutes selected and revised papers presented at the First International Conference on Advancements in Interdisciplinary Research, AIR 2022, held in Allahabad, India, in May 2022. The 49 papers were thoroughly reviewed and selected from the 252 submissions. They are organized in topical sections on novel technologies enabled secured privacy models and optimized networking infrastructures toward secure industries; developments towards sustainable healthcare sector; machine learning and deep learning enabled applications in different sectors; robotics and computer vision for intelligent automation in industries; trending technologies: frameworks and applications focusing real life issues.