Trish obsesses over her best friend's wedding and dramatic weight loss. Robin wants revenge after a lifetime of abuse at the hands of her older sister. Anne is single, lonely, and suffering from obsessive-compulsive disorder. Drug-addicted rock star Louise needs to dry out. Southerner turned wannabe Manhattanite Franny is envious of her neighbors' lives. Sheila wants to punish her boyfriend for returning to his wife. Ellen so desperately wants children that she insists she's pregnant to her disbelieving husband. And Morgan, the hotel manager—haunted by the memory of her dead sister—is the thread that weaves these women's lives together.