Antibacterials

·
· ACS In Focus 12-р ном · American Chemical Society
Электрон ном
100
Хуудас
Боломжит
Үнэлгээ болон шүүмжийг баталгаажуулаагүй  Нэмэлт мэдээлэл авах

Энэ электрон номын тухай

Today, well over 100 commercial antibiotics are available to treat everything from minor nuisances to life-threatening infections, but their indiscriminate use for nonbacterial ailments and agriculture has led to a disturbing trend of antibiotic resistance. Researchers are hard at work searching for new approaches to treat bacterial illnesses in an effort to preserve modern life as we know it.


Antibacterials covers the topics relevant to entering this field of study. We discuss basic bacterial biology and the roles that bacteria play in the world. We also cover the history of antibacterials, both ancient and modern, as well as how commercial antibiotics work on a biochemical level. We examine the interplay between resistance, tolerance, and virulence, the threat that they pose, and ways that scientists are thinking about addressing them. Finally, we provide an overview of the antibacterial development process from initial lead discovery to clinical trials and commercialization.

Зохиогчийн тухай

Ana Victoria Cheng Jaramillo earned her B.A. in chemistry from the New College of Florida in 2017 before beginning her graduate studies in the chemistry department at Emory University. She is currently developing small molecule inhibitors of the bacterial SOS response, work for which she was awarded a Predoctoral National Research Service Award from the National Institutes of Health. She has also been recognized with a NSF Graduate Research Fellowship Program Honorable Mention, Emory Chemistry Quayle Spectrum Scholar Award, and a Science ATL Communication Fellowship. As a queer, Chinese, Colombian, first-generation American, she is passionate about social justice and representation in higher education. She spends her free time skating for Atlanta Roller Derby and spoiling her dog, Pip.

William M. Wuest was born on Long Island, NY in 1981. He obtained his B.S. degree magna cum laude in chemistry/business from the University of Notre Dame (Paul Helquist) in 2003 and a Ph.D. in chemistry from the University of Pennsylvania (Amos B. Smith, III) in 2008. After an NIH NRSA Postdoctoral Fellowship with Christopher T. Walsh at Harvard Medical School, he joined the faculty in the department of chemistry at Temple University as an assistant professor in 2011 where he stayed until 2017 as the Daniel Swern Early Career Development Professor. He moved his research group to Atlanta, GA, where he is currently a Georgia Research Alliance Distinguished Investigator & Associate Professor at Emory University. Research in the Wuest group focuses on the diverted total synthesis of antibacterial natural products. For this, he and his group have received numerous awards including the NSF CAREER Award, ACS Medicinal Chemistry David W. Robertson Award, the ACS Infectious Diseases Young Investigator Award, the New Investigator Award from the Charles E. Kaufman Foundation, and the Italia-Eire Foundation Distinguished Teacher of the Year Award at Temple University.

Энэ электрон номыг үнэлэх

Санал бодлоо хэлнэ үү.

Унших мэдээлэл

Ухаалаг утас болон таблет
Андройд болон iPad/iPhoneGoogle Ном Унших аппыг суулгана уу. Үүнийг таны бүртгэлд автоматаар синк хийх бөгөөд та хүссэн газраасаа онлайн эсвэл офлайнаар унших боломжтой.
Зөөврийн болон ердийн компьютер
Та компьютерийн веб хөтчөөр Google Play-с авсан аудио номыг сонсох боломжтой.
eReaders болон бусад төхөөрөмжүүд
Kobo Цахим ном уншигч гэх мэт e-ink төхөөрөмжүүд дээр уншихын тулд та файлыг татаад төхөөрөмж рүүгээ дамжуулах шаардлагатай болно. Файлуудаа дэмжигддэг Цахим ном уншигч руу шилжүүлэхийн тулд Тусламжийн төвийн дэлгэрэнгүй зааварчилгааг дагана уу.