Antibiotics and Bacterial Resistance

· John Wiley & Sons
Электронная кніга
146
Старонкі
Ацэнкі і водгукі не спраўджаны  Даведацца больш

Пра гэту электронную кнігу

The need for novel antibiotics is greater now than perhaps any time since the pre-antibiotic era. Indeed, the recent collapse of many pharmaceutical antibacterial groups, combined with the emergence of hypervirulent and pan-antibiotic-resistant bacteria has severely compromised infection treatment options and led to dramatic increases in the incidence and severity of bacterial infections.

This collection of reviews and laboratory protocols gives the reader an introduction to the causes of antibiotic resistance, the bacterial strains that pose the largest danger to humans (i.e., streptococci, pneumococci and enterococci) and the antimicrobial agents used to combat infections with these organisms. Some new avenues that are being investigated for antibiotic development are also discussed. Such developments include the discovery of agents that inhibit bacterial RNA degradation, the bacterial ribosome, and structure-based approaches to antibiotic drug discovery.

Two laboratory protocols are provided to illustrate different strategies for discovering new antibiotics. One is a bacterial growth inhibition assay to identify inhibitors of bacterial growth that specifically target conditionally essential enzymes in the pathway of interest. The other protocol is used to identify inhibitors of bacterial cell-to-cell signaling.

This e-book — a curated collection from eLS, WIREs, and Current Protocols — offers a fantastic introduction to the field of antibiotics and antibiotic resistance for students or interdisciplinary collaborators.

Звесткі пра аўтара

Wiley empowers learners, researchers, universities, and corporations to achieve their goals in an ever-changing world. For over 200 years, Wiley has been helping people and organizations develop the skills and knowledge they need to succeed. Wiley develops digital education, learning, assessment, and certification solutions to help universities, businesses, and individuals move between education and employment and achieve their ambitions. By partnering with learned societies, we support researchers to communicate discoveries that make a difference. Our online scientific, technical, medical, and scholarly journals, books, and other digital content build on a 200-year heritage of quality publishing.

Ацаніце гэту электронную кнігу

Падзяліцеся сваімі меркаваннямі.

Чытанне інфармацыb

Смартфоны і планшэты
Усталюйце праграму "Кнігі Google Play" для Android і iPad/iPhone. Яна аўтаматычна сінхранізуецца з вашым уліковым запісам і дазваляе чытаць у інтэрнэце або па-за сеткай, дзе б вы ні былі.
Ноўтбукі і камп’ютары
У вэб-браўзеры камп’ютара можна слухаць аўдыякнігі, купленыя ў Google Play.
Электронныя кнiгi i iншыя прылады
Каб чытаць на такіх прыладах для электронных кніг, як, напрыклад, Kobo, трэба спампаваць файл і перанесці яго на сваю прыладу. Выканайце падрабязныя інструкцыі, прыведзеныя ў Даведачным цэнтры, каб перанесці файлы на прылады, якія падтрымліваюцца.