Mitochondria and Cancer: From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse

Babak Behnam · Maria Vliora · Sumel Ashique · Farhad Taghizadeh-Hesary

Aug 2025 · Elsevier

Ebook

220

Pages

Eligible

This book will become available on August 1, 2025. You will not be charged until it is released.

About this ebook

"MITOCHONDRIA AND CANCER: From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse" is a crucial reference aimed at enhancing the understanding of cancer pathogenesis, therapy resistance, and disease relapse linked to mitochondria. This book merges fundamental scientific knowledge with clinical relevance, presenting recent findings that will engage oncology researchers and provide valuable recommendations for cancer prevention and prognosis. In response to the rising global cancer incidence, this book serves as a comprehensive guide to mitochondrial metabolism in oncology, furthering cancer study and management. It covers a wide range of topics, highlighting the multifaceted role of mitochondria in cancer, including tumor microenvironment, cancer stem cells, microbiota, resistance mechanisms, mitochondria-enhancing strategies, and targeted therapies. Unique topics such as applying magnetic fields to target mitochondria are also discussed, offering novel insights. The manuscript is written at a moderate to advanced technical level, making it suitable for researchers, academics, and professionals in cancer biology, molecular biology, and related fields. It includes technical details, research findings, and discussions on the implications of mitochondrial research in cancer treatment and management. The book's distinguishing aspects include its comprehensive coverage and diverse perspectives from global experts, providing a well-rounded view of current research. This makes "MITOCHONDRIA AND CANCER: From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse" an invaluable resource for anyone seeking to deepen their understanding of the relationship between mitochondria and cancer.• Combines fundamental scientific knowledge with clinical relevance, covering a wide array of topics from mitochondrial metabolism to innovative therapeutic strategies.• Features unique topics such as applying magnetic fields to target mitochondria, offering cutting-edge approaches to cancer treatment and management• Includes contributions from experts across different countries and institutions, providing a well-rounded, global view of current research in mitochondrial involvement in cancer.

About the author

Dr. Babak Behnam has completed his PhD degree at the University College London (UCL) in Human Genetics. Then he served as postdoctoral research fellow at the University of Michigan School of Medicine and University of Central Florida (UCF). He joined the Undiagnosed Disease Program (UDP) at NIH while doing an American Board of Medical Genetics and Genomic in clinical biochemical laboratory genetics at NHGRI, NIH. He joined NSF International as a clinical research organization. Dr. Behnam has published more than 70 peer-reviewed papers and has nine patents to his name throughout his career; also, has served as an Editorial Board Member of several scientific journals. He has enthusiasm in translational research, neuroscience & neurogenetics, and biochemical & molecular mechanisms utilizing advanced technological improvements in biochemical genetics, genomics, and NGS platforms. Also, he has an experience and interest in clinical research, and regulatory and scientific analysis of clinical trials.

Dr. Vliora Maria is a Molecular Biologist with extensive background in molecular biology and integrative physiology. She has previously studied mutations of immunoglobulins in Chronic Lymphocytic Leukemia patients, and ALK mutations and downstream signaling in Neuroblastoma. Dr. Vliora has a PhD in Biomedical Research from University of Thessaly, Greece and University of Brescia, Italy. She has worked on the development of biocompatible/biodegradable bioscaffolds for targeting adipose tissue as well as on potential nanomedical treatments for brain tumors as well as blood malignancies. Her research work is now focusing on environmental influences that can affect human health and on the use of novel biodegradable bio-scaffolds for allografting adipose stem cells in humans. She collaborated with reputable organizations (WHO, ILO) on projects aiming to enhance human health and wellbeing. She now works as a Project Manager on EU funded projects.

Sumel Ashique has been working as an assistant professor at Bengal College of Pharmaceutical Sciences & Research, Durgapur 713212, West Bengal, India, West Bengal, India. He has several years of teaching experience. He has achieved 70+ publications of International and national accredited reputed journals (Scopus, UGC). He has knowledge in drug delivery, nanotechnology and targeted treatment strategy. He has also several granted patents from IP and Australia, a dozen published book chapters in International Books.

Dr. Farhad Taghizadeh-Hesary is an economics and finance associate professor at Tokai University in Japan. He is the co-founder and vice president of the International Society for Energy Transition Studies (ISETS), Editor-in-Chief of the Journal of Environmental Assessment Policy and Management (World Scientific), and associate editor of several academic journals. He has authored over 350 peer-reviewed journal papers and book chapters and edited 25 books by major publishers in various fields, including green finance and sustainability, energy economics, and policy. He was included on Clarivate’s list of Highly Cited Researchers. In 2023, he received the Commendation and Medal for Science and Technology from the Minister of Education, Culture, Sports, Science, and Technology of Japan for his outstanding research achievements. He holds a Ph.D. in economics from Keio University, Japan.

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