Nanobiotechnology: Concepts, Applications and Perspectives
Christof M. Niemeyer · Chad A. Mirkin
Mar 2006 · John Wiley & Sons
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491
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About this ebook
Nanotechnology is the key technology of the 21st century. The possibility to exploit the structures and processes of biomolecules for novel functional materials, biosensors, bioelectronics and medical applications has created the rapidly growing field of nanobiotechnology.
Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments.
It is divided into four main sections:
* Interphase Systems
* Protein-based Nanostructures
* DNA-based Nanostructures
* Nanoanalytics
Each chapter describes in detail currently available methods and contains numerous references to the primary literature, making this the perfect "field guide" for chemists, biologists and materials scientists who want to explore the fascinating world of nanobiotechnology.
Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments.
It is divided into four main sections:
* Interphase Systems
* Protein-based Nanostructures
* DNA-based Nanostructures
* Nanoanalytics
Each chapter describes in detail currently available methods and contains numerous references to the primary literature, making this the perfect "field guide" for chemists, biologists and materials scientists who want to explore the fascinating world of nanobiotechnology.
Ratings and reviews
5.0
2 reviews
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March 17, 2009
The book is really comprehensive with exhaustive material on the subject of nanobiotechnology. The book is principally divided into four main sections. The first section deals with interphase systems pertaining to biocompatible devices for medical implants, microfluidic systems for handling biological components and microelectronic silicon substrates for the investigation of neuronal cells. The second section deals with protein based nanostructures. Various chapters in this section are focussed on use of specific proteins. The microbial production of inorganic nanoparticles and discussion of genetic approaches to generate proteins for organization of nanoparticles instigates the idea of inculcating classical biotechnology into nanobiotechonology.
The third section describes DNA-based nanostructures like DNA protein conjugates, hybrid conjugates of gold nanoparticles and DNA oligomers. the fourth section deals with nanoanalytics which describe number of commercial products in nanobiotechnology. The four chapters describe the use of metal nanoparticles for biolabelling and histochemical applications. Nanoparticles are also employed as carriers for genetic material in non-viral transfection of cells. Two chapters describe the use of scanning probe microscope, the key instrument in nanotechnology for investigating biomolecular structure.
The book combines contributions from analytical, molecular and material science to provide the reader with current and potential developments in nanobiotechnology.
About the author
Christof M. Niemeyer is Professor of Chemistry at the University of Dortmund (Germany) where he holds the chair of Biological and Chemical Microstructuring. He was born in Cloppenburg and studied chemistry at the University of Marburg. He did his thesis at the Max-Planck-Institut fur Kohlenforschung in Mulheim/Ruhr under the supervision of Manfred T. Reetz and his postdoctorate with Charles R. Cantor at the Center for Advanced Biotechnology in Boston (USA). He then went back to Germany, where he worked with Dietmar Blohm at the University of Bremen to complete his habilitation before moving to Dortmund as a full Professor in 2002. He is interested in semisynthetic DNA-protein and -nanoparticle conjugates and their applications in life-sciences, catalysis and molecular nanotechnology.
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Chad A. Mirkin is the George B. Rathmann Professor of Chemistry and the Director of the Institute for Nanotechnology and the Center for Nanofabrication and Molecular Self-Assembly at Northwestern University in Evanston.
Professor Mirkin holds a B.S. degree from Dickinson College (1986) and a Ph.D. degree in chemistry from The Pennsylvania State University (1989). He was a NSF Postdoctoral Fellow at the Massachusetts Institute of Technology before becoming a chemistry professor at Northwestern University in 1991.
Professor Mirkin is known for his development of nanoparticle-based biodetection schemes and his invention of Dip-Pen Nanolithography. He is the founder of two companies, Nanosphere and NanoInk, which are commercializing nanotechnology applications in the life science and semiconductor industries.
Professor Mirkin has been recognized for his accomplishments with the 2004 Nobel Laureate Signature Award for Graduate Education in Chemistry (2003), the 2003 Raymond and Beverly Sackler Prize in the Physical Sciences, the 2002 Feynman Prize in Nanotechnology, the 2001 Leo Hendrick Baekeland Award, the Discover 2000 Award for Technological Innovation, I-Street Magazine's Top 5 List for Leading Academics in Technology, the Materials Research Society Young Investigator Award (2000), the ACS Award in Pure Chemistry (1999), the PLU Fresenius Award (1998), the Harvard University E. Bright Wilson Prize (1998), and the BF Goodrich Collegiate Inventors Award (1997).
******
Chad A. Mirkin is the George B. Rathmann Professor of Chemistry and the Director of the Institute for Nanotechnology and the Center for Nanofabrication and Molecular Self-Assembly at Northwestern University in Evanston.
Professor Mirkin holds a B.S. degree from Dickinson College (1986) and a Ph.D. degree in chemistry from The Pennsylvania State University (1989). He was a NSF Postdoctoral Fellow at the Massachusetts Institute of Technology before becoming a chemistry professor at Northwestern University in 1991.
Professor Mirkin is known for his development of nanoparticle-based biodetection schemes and his invention of Dip-Pen Nanolithography. He is the founder of two companies, Nanosphere and NanoInk, which are commercializing nanotechnology applications in the life science and semiconductor industries.
Professor Mirkin has been recognized for his accomplishments with the 2004 Nobel Laureate Signature Award for Graduate Education in Chemistry (2003), the 2003 Raymond and Beverly Sackler Prize in the Physical Sciences, the 2002 Feynman Prize in Nanotechnology, the 2001 Leo Hendrick Baekeland Award, the Discover 2000 Award for Technological Innovation, I-Street Magazine's Top 5 List for Leading Academics in Technology, the Materials Research Society Young Investigator Award (2000), the ACS Award in Pure Chemistry (1999), the PLU Fresenius Award (1998), the Harvard University E. Bright Wilson Prize (1998), and the BF Goodrich Collegiate Inventors Award (1997).
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