Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds

J. Thomas August · Ferid Murad · M. W. Anders · Wolfgang Dekant

1994년 7월 · Advances in Pharmacology 27권 · Academic Press

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519

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eBook 정보

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.Conjugation reactions have long been associated with the detoxification of xenobiotics. Recent studies suggest that Phase II reactions are an important mechanism for the bioactivation of xenobiotics.This special volume of Advances in Pharmacology features a two-color dust jacket.Summarizes the most recent information on: - Xenobiotic conjugation - Drug toxicity, hypersensitivity, and targeting - Chemical carcinogenesis - Glutathione-, sulfate conjugate-, and glucuranide conjugate-dependent toxicity - Bioactivation and bioconversion

저자 정보

Ferid Murad was born in Whiting, Indiana. Working concurrently on an M.D. and Ph.D. in Pharmacology, Dr. Murad graduated with both degrees from Case Western Reserve University, Cleveland, Ohio, in 1965. His many honors include the Alfred S. Maschke Award for Clinical Excellence from Case Western Reserve University in 1965. He has held several distinguished positions, including Acting Chairman in the Department of Medicine and Acting Division Chief, Division of Respiratory Medicine at Stanford University. He currently is CEO and President of Molecular Geriatrics Corporation in Lake Bluff, Illinois. Dr. Murad is married and has five children.