Interleukin-10
Francesco M. Marincola
Jan 2006 · CRC Press
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Interleukin-10 (IL-10) is regarded as an immune suppressant cytokine. This reputation is due to the experimental observation that IL-10 decreases the function of antigen presenting cells and T helper 1 type immune responses. Surprisingly, however, IL-10 has potent anti-cancer effects since most experimental models demonstrate immune-mediated anti-t
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Francesco M. Marincola, Immunogenetic Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, U.S.A.
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