For each of the following four New Frontiers targets: Ocean Worlds, Trojan Tour and Rendezvous, Io Observer and Lunar Geophysical, this report summarizes changes in scientific understanding or external factors since the release of Vision and Voyages or its midterm review and considers whether those changes have been sufficiently substantial to warrant reconsideration of the four targets for inclusion in the New Frontiers 5 announcement of opportunity, scheduled for release in early 2022.