Over the past decade, providers, policy makers, and stakeholders across a range of disciplines have taken various approaches to addressing the rising incidence of mental, emotional, and behavioral (MEB) health concerns in children and adults. With the recent opioid crisis affecting young people and families across race, ethnicity, and socioeconomic level, and thus adding to the national concern, new efforts and interventions have emerged. However, an overarching system is lacking for the collection of data on these efforts and their efficacy. A strong system for evaluating programs and distributing information could create more opportunities to improve efforts and reduce inefficiencies across programs. Additionally, through engagement of an array of stakeholders from all sectors involved with youth and families, more possibilities for solutions can be realized. To bring together some of these relevant stakeholders and to highlight some of these potential solutions, the National Academies of Sciences, Engineering, and Medicine convened a workshop in October 2019. This publication summarizes the presentations and discussions from the workshop.