Prognostic Epigenetics
Shilpy Sharma
nov 2019 · Translational Epigenetics 15. raamat · Academic Press
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This volume provides comprehensive information on how mapping an individual's epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can be applied in drug development and for better diagnosis and prognosis of diseases. Prognostic Epigenetics is the most-inclusive volume to-date specifically dedicated to epigenetic markers that have been developed for prognosis of diseases, recent advances in this field, the clinical implementation of this research, and the future outlook. - Compiles all known information on prognostic epigenetics and its role in preventive medicine and drug discovery - Covers the basic functionality of epigenetic mechanisms involved in early disease prognosis and diagnosis, and provides tools for the identification and development of these biomarkers for a wide range of diseases - Enables clinicians, researchers, and pharmacologists to improve preventive medicine and precision therapeutics throughout a person's lifetime - Features chapter contributions from leading international researchers
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Dr. Shilpy Sharma, PhD, is an Assistant Professor at the Department of Biotechnology, Savitribai Phule Pune University (Formerly University of Pune) in Pune, Maharashtra, India. She has served as a Post-Doctoral Fellow in the Department of Pharmacology at University of Michigan and as a Post-Doctoral Fellow at the Department of Surgery, University of Chicago Medical Center. Dr. Sharma’s research focuses on identification of prognostic biomarkers for complex disorders including cancer, diabetes, and asthma; and infectious diseases.
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