The book is a comprehensive collection of extended contributions from the Workshops on Computational Optimization 2020. The book includes important real problems like modeling of physical processes, workforce planning, parameter settings for controlling different processes, transportation problems, wireless sensor networks, machine scheduling, air pollution modeling, solving multiple integrals and systems of differential equations which describe real processes, solving engineering problems. It shows how to develop algorithms for them based on new intelligent methods like evolutionary computations, ant colony optimization, constrain programming and others. This research demonstrates how some real-world problems arising in engineering, economics and other domains can be formulated as optimization problems.