The Switch: Activate your metabolism for a healthier life

James W. Clement

Des 2019 · Simon and Schuster

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Enter autophagy, an ancient mechanism built into our cells that eliminates toxic materials, initiates fat-burning, and protects cells against stress. Best-known for being triggered by intermittent fasting, the complex process not only slows down the ageing process, but optimises biological function as a whole, staving off all manner of disease - from diabetes to dementia - and affording us the healthy lifespan we never thought possible.

So how can we activate autophagy? It’s as simple as flipping a switch. The Switch unpacks the revolutionary research on the body's natural process for maintaining health and youthfulness, as well as the “dial” that controls it. Backed by a synthesis of the data, and with a foreword by renowned Harvard geneticists Drs. George Church and David Sinclair, The Switch not only decodes the science of autophagy, but also teaches readers how to control it and benefit from its profound impact.

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James W. Clement is a lawyer and entrepreneur turned research scientist who has devoted the past two decades to understanding the science of life extension. He is best known for his Supercentenarian Research Study, which he started in 2010 with Professor George M. Church of Harvard Medical School. Through worldwide collaborations and in his own laboratory in Gainesville, Florida, he focuses on advancing cutting-edge biomedical discoveries so that humanity can take advantage of these antiaging breakthroughs. Visit him at JamesWClement.com or follow him on Twitter @JamesWClement.

Kristin Loberg has collaborated on a lengthy list of New York Times bestselling books, including Dr. David Perlmutter’s Grain Brain and Dr. David B. Agus’s The End of Illness and A Short Guide to a Long Life.

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