Transgenerational Epigenetics: Edition 2

Trygve O. Tollefsbol

mai 2019 · Translational Epigenetics Bok 13 · Academic Press

E-bok

518

Sider

Kvalifisert

Vurderinger og anmeldelser blir ikke kontrollert Finn ut mer

Om denne e-boken

Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born. This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research. - Presents a fully-updated and expanded release addressing transgenerational epigenetics, epigenetic mechanisms of gene regulation, and the role of epigenetics in human longevity and cancer - Examines the field from "bench-to-bedside", discussing basic science, disease management, current debates, and next steps in epigenetic research and drug discovery - Features chapter contributions from international experts

Om forfatteren

Dr. Tollefsbol is a Distinguished Professor of Biology and a Senior Scientist in the O’Neal Comprehensive Cancer Center, Integrative Center for Aging Research, Nutrition Obesity Research Center, University Wide Microbiome Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999. Dr. Tollefsbol trained as a Postdoctoral Fellow and Assistant Research Professor with members of the National Academy of Science at Duke University and the University of North Carolina. He earned doctorates in molecular biology and osteopathic medicine from the University of North Texas Health Sciences Center and his bachelor’s degree in Biology from the University of Houston. He has received prior funding from the NCI, NHLBI, NIMH and other federal institutes as well as the Glenn Foundation for Medical Research, Susan G. Komen for the Cure, the American Federation for Aging Research (AFAR), and the American Institute for Cancer Research (AICR) among many other sources.

Vurder denne e-boken

Fortell oss hva du mener.

Hvordan lese innhold

Smarttelefoner og nettbrett

Installer Google Play Bøker-appen for Android og iPad/iPhone. Den synkroniseres automatisk med kontoen din og lar deg lese både med og uten nett – uansett hvor du er.

Datamaskiner

Du kan lytte til lydbøker du har kjøpt på Google Play, i nettleseren på datamaskinen din.

Lesebrett og andre enheter

For å lese på lesebrett som Kobo eReader må du laste ned en fil og overføre den til enheten din. Følg den detaljerte veiledningen i brukerstøtten for å overføre filene til støttede lesebrett.

Rapporter ulovlig innhold