Transcriptomics in Atherosclerosis: Deciphering Molecular Signatures and Advancing Therapeutic Strategies

Yvan Devaux’s main research interest and expertise is the discovery and validation of novel RNA biomarkers and therapeutic targets of brain and heart diseases. As his research focus is translational, he believes that collaboration is key: one of his professional goals is to bring together complementary expertise from clinicians, basic researchers, computational biologists, health economists, social sciences and humanities experts, as well as industrial partners to tackle unmet medical needs. His research projects are translational and patient-centered. His team has developed and extensively validated biomarker discovery pipelines based on deep sequencing, bioinformatics approaches, complex statistics, artificial intelligence and machine learning. He is acquainted with coordinating large research projects and consortia. His main current focus is the heart-brain axis and RNA biomarkers of cardiovascular and neurological disease.

Miron Sopić, Ph.D., serves as an Associate Professor in the Department of Medical Biochemistry at the University of Belgrade's Faculty of Pharmacy. His educational contributions span a diverse array of subjects, including General Biochemistry, Biostatistics, and Laboratory Diagnostics, highlighting his broad expertise in the field. Sopić's research endeavors are centered on investigating the intricate interactions between inflammation and oxidative stress in cardiometabolic diseases, with a particular focus on identifying and developing novel RNA biomarkers. His prolific academic output includes more than 41 scientific papers. In 2022, Miron Sopić was honored with the esteemed MSCA Postdoctoral Fellowship, which facilitated his collaboration with Yvan Devaux on researching epitranscriptomic signatures in atherosclerosis at the Cardiovascular Research Unit of the Luxembourg Institute of Health.