Physicalism—the thesis that everything there is in the world, including our minds, is constituted by basic physical entities—has dominated the philosophy of mind during the last few decades. But although the conceptual foundations of the physicalist agenda—including a proper explication of notions such as ‘causation', ‘determination', ‘realization’ or even ‘physicalism’ itself—must be settled before more specific problems (e.g. the problems of mental causation and human agency) can be satisfactorily addressed, a comprehensive philosophical reflection on the relationships between the various key concepts of the debate on physicalism is yet missing. This book presents a range of essays on the conceptual foundations of physicalism, mental causation and human agency, written by established and leading authors in the field.