This paper proposes a modified structure for the neutrosophic set called the Quantified Neutrosophic Set (QtNS) with a parameterized setting. Unlike conventional approaches, the QtNS provides a quantified environment for the indeterminacy by its dependence on truthness and falsity components. This innovative approach quantifies the uncertainty and improves the assessment process via expert-guided opinions, customising it according to the specific situations in real-world decision-making scenarios. Some QtNS operations along with useful characteristics are addressed. Furthermore, two algorithms, QtNSUI and QtNSAO, are developed for the proposed operations of union, intersection, AND, and OR based on QtNS. In the world of sustainable materials, biofabricated textiles are making progress. The MCDM methods based on QtNS are developed for material preferences in the industry of biofabricated textiles, specifically with anti-microbial properties. The study’s main purpose is to develop a novel technique to quantify and reduce the predicted uncertainties in the material preference problem for antimicrobial biofabricated textile manufacturing. For eco-conscious decision-making, our work would provide an optimised environment at the industrial level, especially for ecologically conscious textile industries, for enhanced and sustainable selection with greater accuracy.