Ernst Hadorn was a Swiss developmental biologist. He developed techniques for imaginal disc transplantation in Drosophila, leading to technique for the production of fate maps, and studied the organization of mature discs. He discovered the phenomenon of transdetermination. Hadorn was noted for both his experimental skills and teaching.
Hadorn was born in the family of farmers in Forst in Bernese Oberland. Even as a child he was interested in the development of frogs from their eggs each summer. He worked as a teacher in a local village and earned enough money to study biology at the University of Berne under Fritz Baltzer studying nuclear-cytoplasmic interactions. He received a PhD in 1931 and began to teach graduate students. He began to conduct research in his basement on amphibia and with Baltzer's encouragement he applied for a Rockefeller fellowship and went to University of Rochester and met Curt Sturn and began to work with Drosophila. He returned to Switzerland and later joined the University of Zurich where he worked until 1972.