Neuroimaging Genetics: Principles and Practices

Kristin L. Bigos · Ahmad R. Hariri · Daniel R. Weinberger

2016年2月 · Oxford University Press

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The field of neuroimaging genetics has grown exponentially over the past decade. To date there are more than 10,000 published papers involving MRI, PET, MEG and genetics. Neuroimaging Genetics: Principles and Practices is the comprehensive volume edited by Drs. Bigos, Hariri, and Weinberger and co-authored by the preeminent scholars in the field. This text reviews the basic principles of neuroimaging techniques and their application to neuroimaging genetics. The work presented in this volume elaborates on the explosive interest from diverse research areas in psychiatry and neurology in the use of imaging genetics as a unique tool to establish and identify mechanisms of risk, establish biological significance, and extend statistical evidence of genetic associations. Examples throughout highlight the application of imaging genetics to understand neurochemical systems and pathways, explore relationships between genetics and the structural and functional connectivity in human brain, and provide insight into mechanisms of risk for psychiatric and neurologic illness.

作者简介

Kristin L. Bigos is Investigator at the Lieber Institute for Brain Development and Assistant Professor of Medicine in the Division of Clinical Pharmacology at Johns Hopkins School of Medicine. Ahmad R. Hariri is a Professor in the Department of Psychology and Neuroscience at Duke University. Daniel R. Weinberger is Director and CEO at the Lieber Institute for Brain Development and Professor of Psychiatry and Behavioral Sciences at Johns Hopkins School of Medicine.