Sex Differences in Neurology and Psychiatry

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· Handbook of Clinical Neurology Buku 175 · Elsevier
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Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. - Explores sex differences in human neuroanatomy and neurophysiology - Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders - Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context

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Dr. Lanzenberger’s research areas include multimodal neuroimaging using PET and fMRI in both psychiatric and neurological patients in comparison to healthy controls, neuroimaging in psychopharmacology, psychoneuroendocrinology including gender medicine, cognitive neuroscience, genetic neuroimaging and experimental neuronuclear medicine. Recently, new multimodal neuroimaging approaches combining pharmacological MRI (phMRI) and PET have been developed. These methodological advancements allow for the evaluation of drug effects in the brain of healthy subjects and patients. By combining molecular and functional imaging information regarding relationship between neurochemical, structural and functional alterations in psychiatric and neurological disorders may be gleaned.

Georg S. Kranz works at The Hong Kong Polytechnic University, Department of Rehabilitation Sciences, Hong Kong, SAR, China, and at the Medical University of Vienna, Department of Psychiatry and Psychotherapy, Division of General Psychiatry, NEUROIMAGING LABs (NIL) - PET, MRI, EEG, TMS and Chemical Lab, Vienna, Austria.

Dr. Savic’s group is a member of the Stockholm Brain Institute (SBI), a center at the Karolinska Institute for Cognitive and Computational Neuroscience. Her research focuses on the cognitive and emotional decline related to chronic stress as a recognized phenomenon and understanding the underlying mechanisms. They are applying several brain imaging techniques, including PET, to investigate how the human brain is affected by psychosocial stress, and explain the reported emotional and cognitive decline related to stress. The aim is to find biochemical markers of chronic psychosocial stress and develop new treatment strategies.

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