Electric Field-Induced Effects on Neuronal Cell Biology Accompanying Dielectrophoretic Trapping
Dec 2012 · Advances in Anatomy, Embryology and Cell Biology Book 173 · Springer Science & Business Media
Ebook
80
Pages
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About this ebook
The concept of the cultured neuron probe was induced by the possible selective stimulation of nerves for functional recovery after a neural lesion or disease. The probe consists of a micro-electrode array on top of which groups of neuronal cells are cultured. An efficient method to position groups of neuronal cells on top of the stimulation sites of the micro-electrode array is developed. With negative dielectrophoretic forces, produced by non-uniform electric fields on polarizable particles, neuronal cells are trapped. Experimental results and model simulations describe the trapping process and its effect on neuronal cell viability.
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